研究業績

書籍、レビュー論文、原著論文、学会発表など

最近の業績の一部を挙げています。
さらに過去の文献や講演に関する情報については「業績一覧」のページをご覧ください。


書籍、レビュー論文

  • 下島公紀,岡村慶,藤井輝夫:"熱水探査のための化学・生物センサの開発状況と今後の開発ならびに民間移転に向けた取り組み",海洋調査技術,Vol.30(2018),pp.35-43.
  • 金秀炫,伊藤博史,藤井輝夫:"血中循環腫瘍細胞の高純度分離・1 細胞解析を実現する新規システム",PHARM STAGE,Vol.17,No.9(2017),pp.26-30.
  • 木村啓志,南学正臣,藤井輝夫:"Organ-on-a-Chip の潮流とin vitro 腎臓モデルデバイスへの応用",腎臓内科・泌尿器科,Vol.5,No.5(2017),pp.504-508.
  • 松尾司,木下晴之,大島まり,藤井輝夫:"デジタルホログラフィを用いたリアルタイム三次元計測器の開発とその応用",光アライアンス,Vol.28,No.2(2017),pp.30-34.
  • 木下晴之,前川敏郎,国田勝行,黒田真也,藤井輝夫:"細胞応答計測のためのマイクロ流体制御技術と細胞培養",臓器チップの技術と開発動向,システム/制御/情報,Vol.61,No.7( 2017),pp.253-258.
  • 木村啓志,藤井輝夫:"臓器チップ開発のための微細加工技術",臓器チップの技術と開発動向,シーエムシー出版(2017),pp.31-36.
  • 伊藤博史,金秀炫,藤井輝夫:"第2章 誘電泳動を用いた細胞濃縮デバイスを組み込んだCTC高純度濃縮システム",リキッドバイオプシー ―体液中腫瘍マーカーの検出・解析技術―,シーエムシー出版(2017).
  • 藤井輝夫:"社会ニーズと技術シーズの融合を実現するデザイン未来像",生産研究,Vol.69,No.5(2017),pp.229-231.
  • 木村啓志,酒井康行,藤井輝夫:"マイクロ流体デバイス技術によるOrgan/Body-on-a-Chipの実現に向けた取り組み",細胞,Vol.43, No.3 (2016),pp.44-47.
  • 藤井輝夫:"年頭所感",生産研究,Vol.68, No.1 (2016),pp.1-2.
  • 木村啓志,酒井康行、藤井輝夫:"マイクロ流体デバイス技術によるOrgan/Body-on-a-Chipの実現に向けた取り組み",細胞,Vol.43, No.3 (2016) pp.44-47.
  • 木村啓志,藤井輝夫,酒井康行:"創薬を加速化するツールとしてのOrgan-on-a-chip の進展",薬剤学,Vol.76, No.4 (2016) pp.238-242.
  • 小森喜久夫,木村啓志,藤井輝夫,酒井康行:"細胞アッセイ応用を指向した生理学的応答を示す臓器・生体モデルの開発",化学センサ,Vol.3,No.3 (2016) pp.104-110.
  • 川田治良,藤井輝夫,池内与志穂:"神経変性疾患の理解と治療に向けた研究の概況と新しいアプローチ",生産研究,Vol.68,No.3(2016),pp.25-30.
  • Kawada, J., Kaneda, S., Kim, S.-H., and Fujii, T.: "Microfluidic Approach to Cell Handling and Measurement", Tsuji, S., and Sone, J. eds., Intelligent Nanosystems for Innovations in Energy, Environment, and Biotechnologies, Springer (2016), pp.85-106
  • 福場辰洋,花谷耕平,藤井輝夫:"マイクロ流体デバイス技術を応用した現場計測システム",光アライアンス,Vol.26,No.5 (2015),pp.7-11.
  • 福場辰洋,西田周平,藤井輝夫:"可搬型装置が拓く資源探査・海洋科学の新時代",化学工学誌,Vol.79,No.2 (2015),pp.125-127.
  • 藤井輝夫:"『「いきもの」に学ぶ工学』所長挨拶",生産研究,Vol.67,No.5 (2015),pp.1-3.
  • ナタリーフランセス,金範?,藤田博之,エリックラルティゴー,藤井輝夫,ドミニクコラール:"Sendng Microsystems in Medicine in Lille – European Japanese Technologies against Cancer A blank is missing (SMMiL-E)",生産研究,Vol.67,No.5 (2015),pp.131-134.
  • ティモテレヴィ,藤井輝夫:"Microfluidic device that mimics neurons",生産研究,Vol.67,No.5 (2015),pp.135-137.
  • アレクサンドルバクーシュ,藤井輝夫,ヤニックロンドレーズ,アントニージュノ:"Molecular programming and microsystems",生産研究,Vol.67,No.5 (2015),pp.169-175.
  • Fukuba, T., Noguchi, T., and Fujii, T.: "The Yoron Hole: The Shallowest Hydrothermal System in the Okinawa Trough", J. Ishibashi, K. Okino, and M. Sunamura eds., Subseafloor Biosphere Linked to Hydrothermal Systems - TAIGA Concept, Springer (2015), pp.489-492, DOI: 10.1007/978-4-431-54865-2_38
  • Fukuba, T., Noguchi, T., and Fujii, T.: "The Irabu Knoll: Hydrothermal Site at the Edge of the Yaeyama Graben", J. Ishibashi, K. Okino, and M. Sunamura eds., Subseafloor Biosphere Linked to Hydrothermal Systems - TAIGA Concept, Springer (2015), pp.493-496, DOI: 10.1007/978-4-431-54865-2_39
  • Noguchi, T., Fukuba, T., Okamura, K., Ijiri, A., Yanagawa, K., Ishitani, Y., Fujii, T., and Sunamura, M.: "Distribution and Biogeochemical Properties of Hydrothermal Plumes in the Rodoriguez Triple Junction", J. Ishibashi, K. Okino, and M. Sunamura eds., Subseafloor Biosphere Linked to Hydrothermal Systems - TAIGA Concept, Springer (2015), pp.195-204,DOI: 10.1007/978-4-431-54865-2_15

原著論文

  • Kim, S. H., Ito, H., Kozuka, M., Takagi, H., Hirai, M., and Fujii, T.: "Cancer marker-free enrichment and direct mutation detection in rare cancer cells by combining multi-property isolation and microfluidic concentration", Lab on a Chip, Vol.19, No.5 (2019), pp.757-766.
  • 立川冴子,金田祥平,久米村百子,佐藤竜偉,塚本拓野,藤井輝夫,鈴木孝明,藤田博之:"三次元立体露光法を用いて作製したがん細胞浸潤過程観察用マイクロ流体デバイス",電気学会論文誌E,Vol.138,No.9(2018),pp.435-440.
  • Yamanaka, H., Komeya, M., Nakamura, H., Sanjo, H., Sato, T., Yao, M., Kimura, H., Fujii, T., and Ogawa, T.: "A monolayer microfluidic device supporting mouse spermatogenesis with improved visibility”, Biochemical and Biophysical Research Communications, Vol.500 (2018), pp.885-891.
  • Matsumoto, S., Leclerc, E., Maekawa, T., Kinoshita, H., Shinohara, M., Komori, K., Sakai, Y., and Fujii, T.: "Integration of an oxygen sensor into a polydimethylsiloxane hepatic culture device for two-dimensional gradient characterization”, Sensors and Actuators B: Chemical, Vol.273 (2018), pp.1062-1069.
  • Fukuba, T., Noguchi, T., Okamura, K., and Fujii, T.: "Adenosine triphosphate measurement in deep sea using a microfluidic device", Micromachine, Vol.9, No.8 (2018), 370.
  • Nishikawa, S. M., Kim, S.-H., Luo, Z., Kirihara, T., Ikeuchi, Y., Fujii, T., and Levi, T.: "Biomimetic microfluidic neurons for bio-hybrid experiments", Artificial Life and Robotics, Vol.23 (2018), pp.402-408.
  • Kojima, K., Nakamura, H., Komeya, M., Yamanaka, H., Makino, Y., Okada, Y., Akiyama, H., Torikai, N., Sato, T., Fujii, T., Kimura, H., and Ogawa, T.: "Neonatal testis growth recreated in vitro by two-dimensional organspreading", Biotechnology and Bioengineering, Vol.115 (2018), pp.3030-3041.
  • Oishi, M., Kinoshita, H., Fujii, T., and Oshima, M.: "Phase-locked confocal micro-PIV measurement of three-dimensional flow structure transient droplet formation mechanism in T-shaped micro junction", Measurement Science and Technology, Vol.29 (2018), 115204.
  • Kimura, H., Sakai, Y., and Fujii, T.: "Organ/body-on-a-chip based on microfluidic technology for drug discovery", Drug Metabolism and Pharmacokinetics, Vol.33 (2018), pp.43-48.
  • Kim, S. H., Ito, H., Kozuka, M., Hirai, M., and Fujii, T.: "Localization of low-abundant cancer cells in a sharply expanded microfluidic step-channel using dielectrophoresis", Biomicrofluidics, Vol.11 (2017), 054114.
  • Shinohara, M., Komori, K., Fujii, T., and Sakai, Y.: "Enhanced self-organization of size-controlled hepatocyte aggregates on oxygen permeable honeycomb microwell sheets", Biomedical Physics & Engineering Express, Vol.3 (2017), 45016.
  • Komeya, M., Hayashi, K., Nakamura, H., Yamanaka, H., Sanjo, H., Kojima, K., Sato, T., Yao, M., Kimura, H., Fujii, T., and Ogawa, T.: "Pumpless microfluidic system driven by hydrostatic pressure induces and maintains mouse spermatogenesis in vitro", Scientific Reports, Vol.17 (2017), 15459.
  • Kawada, J., Kaneda, S., Kirihara, T., Maroof, A., Levi, T., Eggan, K., Fujii, T., and Ikeuchi, Y.: "Generation of a motor nerve organoid with human stem cell-derived neurons", Stem Cell Reports, Vol.9, No.5 (2017), pp.1441-1449.
  • Baccouche A., Okumura S., Sieskind R., Henry E., Aubert-Kato N., Bredeche N., Bartolo JF., Taly V., Rondelez Y., Fujii T., Genot A. J.: "Massively parallel and multiparameter titration of biochemical assays with droplet microfluidics", Nature Protocols 12, 1912 (2017), doi:10.1038/nprot.2017.092.
  • Kaneda, S., Kawada, J., Akutsu, H., Ichida, J., Ikeuchi, Y., and Fujii, T.: "Compartmentalized embryoid body culture for induction of spatially patterned differentiation", Biomicrofluidics, Vol.11 (2017), 041101.
  • Gines, G., Zadorin, A., Galas, J.-C., Fujii, T., Extevez-Torres, A., and Rondelez, Y.: "Microscopic Agents Programmed by DNA Circuits", Nature Nanotechnology (2017), advanced online publication, doi:10.1038/nnano.2016.299
  • Leclerc, E., Kimura, K. Shinohara, M., Mathies D., Le Gall, M., Kido, A., Miyajima, A., Fuii, T. Sakai, Y.: "Comparison of the Transcriptomic Profile of Hepatic Human induced Pluripotent Stem like Cells Cultured in Petri and in a 3D Microscale Dynamic Environment", Genomics, Vol.109 (2017), pp.16-26
  • Antfolk, M, Kim, S.-H., Koizumi, S., Fujii, T., and Laurell, T.: "Label-free single-cell separation and imaging of cancer cells using an integrated microfluidic system", Scientific Reports (2017), 7:46507 | DOI: 10.1038/srep46507
  • Komeya, M., Hiroshi Kimura, H., Nakamura, H., Yokonishi, T., Sato, T., Kojima, K., Hayashi, K., Katagiri, K., Yamanaka, H., Sanjo, H., Yao, M., Kamimura, S., Inoue, K., Ogonuki, N., Ogura, A., Fujii, T., and Ogawa, T.: "Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device", Sci Rep., Vol. 19(6) (2016), pp. 2147232(8).
  • Perret, G., Ginet, P., Tarhan, M. C., Baccouche, A., Lacornerie, T., Kumemura, M., Jalabert, L., Cleri, F., Lartigau, E. F., Kim, B. J., Karsten, S. L., Fujita, H., Rondelez, Y., Fujii, T., and Collard, D.: "Nano systems and devices for applications in biology and nanotechnology", Solid-State Electronics, Vol.115 (2016), pp.66-73.
  • Kim, Y.J., Kim, S.H., Fujii, T., and T. Matsunaga, Y.: "Dual Stimuli-Responsive Smart Beads that allow "On-Off" Manipulation of Cancer Cells", Biomaterials Science, Vol.4 (2016), pp.953-957.
  • Kim, S.-H., and Fujii, T.: "Efficient Analysis of a Small Number of Cancer Cells at the Single-cell Level using Electroactive Double-well Array", Lab on a Chip, Vol.16 (2016) pp.2440-2449, featured as Front Cover, p.2351, DOI: 10.1039/C6LC90066F
  • Genot, A., Baccouche, A., Sieskind, R., Aubert-Kato, N., Bredeche, N., Bartolo, J.-F. Taly, V., Fujii, T., and Rondelez, Y.: "High-resolution mapping of bifurcations in nonlinear biochemical circuits", Nature Chemistry, Vol.8 (2016), pp.760-767.
  • Park, J.-W., Kim, S.-H., Ito, T., Fujii, T., Kim, S.-Y., Laurell, T., Lee, S.-W. and Goda, K.: "Acoustofluidic harvesting of microalgae on a single chip", Biomicrofluidics, Vol.10 (2016), 034119.
  • Levi, T., and Fujii, T.: "Microfluidic neurons, a new way in neuromorphic engineering?", Micromachines, Vol.7 (2016), 146, doi:10.3390/mi7080146.
  • Montagne, K., Gines, G., Fujii, T., and Rondelez, Y.: "Boosting functionality of synthetic DNA circuits with tailored deactivation", Nature Communications, Vol.7 (2016), 13474, DOI: 10.1038/ncomms13474
  • Horayama, M., Kabayama, K., Fujii, T., and Kimura, H.: "Spatial Chemical Stimulation Control in Microenvironment by Microfluidic Probe Integrated Device for Cell-based Assay", PLoS ONE, Vol.11, No.12 (2016), e0168158. doi:10.1371/journal. pone.0168158
  • Kim, S. H., Antfolk, M., Kobayashi, M., Kaneda, S., Laurell, T., and Fujii, T.: "Highly efficient single cell arraying by integrating acoustophoretic cell pre-concentration and dielectrophoretic cell trapping", Lab on a Chip, Vol.15 (2015), pp.4356-4365.
  • Kobayashi, M., Kim, S. H., Nakamura, H., Kaneda, S., and Fujii, T.: "Cancer cell analyses at the single cell-level using electroactive microwell array device", PLoS ONE, Vol.10(11) (2015), e0139980, pp.1-11.
  • Provin, C., Nicolas, A., Grégoire, S., and Fujii, T.: "A Microfluidic Diffusion Cell for Fast and Easy Percutaneous Absorption Assays", Pharm Res, Vol. 32(8) (2015), pp.2704-12.
  • Tozawa, H., Maekawa, T., Sakai, T., and Fujii, T.: "A novel effect of parylene-based surface coating on HepG2 cell func- tion", Materials Science and Engineering C, Vol.46 (2015), pp.190-194.

招待講演、依頼講演

  • 藤井輝夫:"第3期海洋基本計画を進めるために",日本海洋政策学会創立10周年記念シンポジウム,東京(2018).
  • 金秀炫,藤井輝夫:"希少細胞の高効率1細胞解析を可能とするElectroactive Microwell Array の開発",第2回Liquid Biopsy研究会,東京(2018).
  • Fujii, T.: "Innovative Microfluidic Platforms − from Single-cell Analysis to Molecular Systems", The 10th International Symposium on Microchemistry and Microsystems (ISMM2018), Busan, Korea (2018).
  • 藤井輝夫:"Organ-on-a-Chip:マイクロ流体アプローチが拓く新展開",第114回日本内科学会総会,東京(2017).
  • Fujii, T.: "Microfluidics for Innovative Biological Experimentations − from Single Cell Analysis to Organ-on-a-Chip", The 9th International Symposium on Microchemistry and Microsystems (ISMM 2017), Tasmania, Australia (2017).
  • Fujii, T.: "Microfluidics as Innovative Technology for Biological Experimentations", The 3rd Symposium Max Planck-the University of Tokyo Center for Inflammology, Berlin, Germany (2016).
  • 金田祥平:"細胞培養・分離・解析用マイクロ流体技術",次世代マイクロ化学チップコンソーシアム第37回研究会,東京 (2016).
  • 藤井輝夫:"マイクロ流体デバイス技術が拓く医療バイオ分野の新展開",第12回骨免疫ワークショップ,東京 (2016).
  • 藤井輝夫:"Small Meets Large: Connecting Microfluidics with Marine Ecology",OISTミニシンポジウム,沖縄 (2015).
  • 藤井輝夫:"マイクロ流体デバイスを用いた細胞培養技術",筋萎縮性側索硬化症(ALS)新規治療法開発をめざした病態解明平成27年度ワークショップ,東京 (2015).
  • 藤井輝夫:"細胞・組織工学のための高解像度バイオ技術",ライフサイエンス技術部会材料分科会講演会,東京 (2015).

学会発表

  • Lobato-Dauzier, N., Deteix, R., Fujii, T., and Genot, A. J.: "Silicon droplet chamber for quantitative imaging of biochemical systems", 第2回分子ロボティクス年次大会,東京(2019).
  • 奥村周,A. Genot,藤井輝夫:"PEN DNA toolbox を利用したDNA 濃度パターンの線形分離システムの構築",第2回分子ロボティクス年次大会,東京(2019).
  • Nishikawa, S. M., Khoyratee, F., Kim, S. H., Ikeuchi, Y., Aihara, K., Fujii, T., and Levi, T.: "Biomimetic spike-timing based ionic microstimulation for neuron culture", ICAROB, Beppu, Japan (2019), p.4.
  • Baccouche, A., Rondelez, Y., Fujii, T., and Genot, A.: "Seeing the shape of a molecular program", Active Matter Workshop 2019, Tokyo, Japan (2019).
  • Lobato-Dauzier, N., Gines, G., Rondelez, Y., Fujii, T., and Genot, A. J.: "MEGABOTS: DNA nano-robots swarms for multiscale dynamic construction", Active Matter Workshop 2019, Tokyo, Japan (2019).
  • Hapsianto, B. N., Maekawa, T., Kurita, R., Kim, S. H., and Fujii, T.:"Hybridization-free DNA capture beads for cfDNA-capture",Liquid Biopsy研究会,東京(2019).
  • 土肥浩太郎,木村啓志,南学正臣,藤井輝夫:"温度感受性不死化ポドサイトにおける入り組む樹状突起構造の再現",第3回ポドサイト研究会,東京(2019),p.28.
  • Kim, S. H., Yoshida, M., Tago, S., and Fujii, T.: "Efficient pairing of single cells using trap-and-drop microwell array", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan (2018), pp.243-244.
  • Okumura, S., Fujii, T., and Genot, A.: "Multi-strands responsive DNA hydrogel beads fabricated with microfluidics", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan (2018), pp.636-637.
  • Matsumoto, S., Leclerc, E., Safitri, A. R., Danoy, M., Maekawa, T., Kinoshita, H., Shinohara, M., Komori, K., Sakai, Y., and Fujii, T.: "Recapitulation of rat hepatocellular function forming oxygen gradient in a microfluidic cell culture device”, Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan (2018), pp.1573-1574.
  • Nishikawa, S. M, Khoyratee, F., Luo, Z., Shiraishi, T., Aihara, K., Ikeuchi, Y., Kim, S. H., Fujii, T., and Levi, T.: "Neuro-hybrid system with spiking neural network and biomimetic ionic micro-stimulation", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan (2018), pp.1688-1689.
  • Fukuba, T., Nakasa, A. Tsukada, O., and Fujii, T.: "Application of drug infusion balloons to microfluidic systems for in situ measurement", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan (2018), pp.2281-2282.
  • Park, C. J., Kim, S. H., and Fujii, T.: "Electroactive microwell array for separate trapping of single cells and clusters", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan (2018), pp.2461-2462.
  • Matsumoto, S., Leclerc, E., Maekawa, T., Kinoshita, H., Shinohara, M., Komori, K., Sakai, Y., and Fujii, T.: "Visualization of the difference of rat hepatocellular function under oxygen gradient", Proceedings of the 10th International Symposium on Microchemistry and Microsystems (ISMM 2018), Busan, Korea (2018).
  • Okumura, S., Feray, C., Zheng, M., Tanabe, Y., Oba, M., Kusanagi, T., Kobayashi, S., Takada, K., Bennar, S., Yonetuka, H., Wake, T., Genot, A. J., and Fujii, T.: "Logic gated hydrogel”, Proceedings of the 10th International Symposium on Microchemistry and Microsystems (ISMM 2018), Busan, Korea (2018).
  • Nishikawa, S. M., Kim, S. H., Ikeuchi, Y., Fujii, T., and Levi, T.: "Biomimetic ionic microstimulation for neuron culture”, Proceedings of the 10th International Symposium on Microchemistry and Microsystems (ISMM 2018), Busan, Korea (2018).
  • 奥村周,田邊由佳,大庭ジーナ未来,草彅達也,小林新九郎,髙田和輝,ベナー聖樹,米塚広樹,和氣拓海,A. Genot,藤井輝夫:"ストランド応答性DNA ハイドロゲルの開発",化学とマイクロ・ナノシステム学会第37回研究会(37th CHEMINAS)講演要旨集,つくば(2018),p.98.
  • 松本倫実,E. Leclerc,前川敏郎,木下晴之,篠原満利恵,小森喜久夫,酒井康行,藤井輝夫:"In vitro における肝機能変化の酸素濃度依存性に関する検証",化学とマイクロ・ナノシステム学会第37回研究会(37th CHEMINAS)講演要旨集,つくば(2018),p.102.
  • 孫明玥,吉富匠,木村啓志,金秀炫,藤井輝夫:"3Dプリンタで製作したマイクロ流体デバイスを用いる生体機能チップのモジュール化",化学とマイクロ・ナノシステム学会第38回研究会(38th CHEMINAS)講演要旨集,札幌(2018),p.79.
  • Baccouche, A., Fujii, T., and Genot, A.: "Kinetic study of CRISPR-Cas9 for dynamic DNA nanotechnology", Functional DNA Nanotechnology Workshop, Rome, Italy (2018).
  • Lobato-Dauzier, N., Aubert-Kato, N., Vlandas, A., Fujii, T., and Genot, A.: "Shape recognition using chemical networks”, JFR 2018: Journée Francophone de la recherche, Tokyo, Japan (2018).
  • Kim, S. H., Yoshida, M. and Fujii, T.: "Label-free selective trapping of single cancer cells using electroactive microwell array", Book of abstracts of AMN / ISMM / APCBM / ANZNMF joint conference, Tasmania, Australia (2017).
  • Matsumoto, S., Leclerc, E., Maekawa, T., Kinoshita, H., Shinohara, M., Komori, K., Sakai, Y., and Fujii, T.: "Position-selective cell sampling using localized trypsin streams", Book of abstracts of AMN / ISMM / APCBM / ANZNMF joint conference, Tasmania, Australia (2017).
  • Matsumoto, S., Leclerc, E., Maekawa, T., Kinoshita, H., Shinohara, M., Komori, K., Sakai, Y., and Fujii, T.: "Position-selective cell sampling microfluidic system using localized laminar flows", Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah, USA (2017), pp.1131-1132.
  • Kim, S. H., Mitsunaka, T., Fujimoto, Y., Iizuka, K., and Fujii, T.: "Addressable electroactive microwell array capable of deterministic combinatorial trapping of single cells", Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah, USA (2017), pp.120-121.
  • Kim, S. H., Ito, H., Kozuka, M., Takagi, H., Hirai, M., and Fujii, T.: "Highly efficient rare cancer cells isolation and concentration by combining label-free isolation and dielectrophoretic concentration in a microfluidic step-channel", Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah, USA (2017), pp.197-198.
  • Takeuchi, M., Kim, S. H., Nagasaka, K., Yoshida, M., Kawata, Y., Oda, K., and Fujii, T.: "Highly efficient trapping and analysis of rare cells using an electroactive microwell array with barriers", Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah, USA (2017), pp.880-881.
  • 松本倫実,E. Leclerc,前川敏郎,木下晴之,篠原満利恵,小森喜久夫,酒井康行,藤井輝夫:"肝細胞培養デバイスにおけるトリプシンを用いた局所的細胞回収方法の検討",2017年度精密工学会春季大会学術講演会講演論文集,横浜(2017),pp.351-352.
  • 伊藤博史,金秀炫,小塚昌弘,髙木英紀,平井光春,藤井輝夫:"新規誘電泳動デバイスを組込んだCTC 高純度濃縮システムの開発",化学とマイクロ・ナノシステム学会第35回研究会(35th CHEMINAS)講演要旨集,東京(2017),p.109.
  • 金秀炫,満仲健,藤本義久,飯塚邦彦,藤井輝夫:"Addressable Electroactive Microwell Arrayで実現する単一細胞の組み合わせ",化学とマイクロ・ナノシステム学会第36回研究会(36th CHEMINAS)講演要旨集,群馬(2017),p.22.
  • 小森隆幸,金秀炫,宇田徹,藤井輝夫:"希少細胞の解析に向けた細胞分離・捕捉デバイス",化学とマイクロ・ナノシステム学会第36回研究会(36th CHEMINAS)講演要旨集,群馬(2017),p.40.
  • Kim, S. H., Mitsunaka, T., Fujimoto, Y., Iizuka, K. and Fujii, T.: "Highly efficient compartmentalization of multiple single cells using addressable electroactive microwell array", 2017 meeting on Single Cell Analyses, Cold Spring Harbor Laboratory, NY, USA (2017), p.24.
  • Kaneda,S., Kawada, J., and Fujii, T.: "Immobilization of tumor spheroid on a through-hole membrane to mimic tumor microenvironment", Proceedings of IEEE EMBS Conference on Micro and Nanotechnology in Medicine 2016, Hawaii, USA (2016), P40.
  • Ono, T., Fujii, T., Sakai, Y., and Kimura, H.: "Development of organs-on-a-chip with metabolism model", Proceedings of the 27th International Symposium on Micro-NanoMechatronics and Human Science (MHS 2016), Nagoya, Japan (2016).
  • Drame-Maigne, A., Amikura, K., Kiga, D., Fujii, T., and Rondelez, Y.: "Artificial networks implementing selection functions for directed evolution", Proceedings of DNA22, Munich, Germany (2016).
  • Nishida, S., Matsubara, N., Fukuba, T., Kyo, M., and Fujii, T.: "Underwater atomic force microscope", Proceedings of 24th International Colloquium on Scanning Probe Microscopy (ICSPM 24), Hawaii, USA (2016), S4-60.
  • Nishida, S., Matsubara, N., Fukuba, T., Kyo, M., and Fujii, T.: "Underwater atomic force microscope: Instrumentation, operation, and measurement", Proceedings of Techno-Ocean 2016, Kobe, Japan (2016), 4B.3.
  • Nishida, S., Matsubara, N., and Fujii, T.: "Underwater atomic force microscope: Development and in situ testing in deep sea", Proceedings of OCEANS 2016 Monterey, Monterey, USA (2016), p. 91.
  • Ito, H., Takagi, H., Kozuka, M., Kim, S. H., Hirai, M., and Fujii, T.: "Genetic testing by a novel high-purity concentration system for circulating tumor cells independent of epithelial markers", Proceedings of EUROPEAN SOCIETY FOR MEDICAL ONCOLOGY 2016 Congress, Copenhagen, Denmark (2016), 1160P.
  • Matsumoto, S., Leclerc, E., Maekawa, T., Kinoshita, H., Shinohara, M., Komori, K., Sakai, Y., and Fujii, T.: "Creation and visualization of oxygen concentration in a microfluidic hepatocytes culture device”, Proceedings of 8th International Symposium on Microchemistry and Microsystems (ISMM 2016), Hong Kong (2016), 02c1.
  • Ogata, K., Kim, S. H., and Fujii, T.: "Electroactive trap-well array coupled with PDMS reaction-well array allows highly efficient single-cell trapping followed by on-chip analysis with a controllable dilution ratio of cell lysates", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.335-336.
  • Matsumoto, S., Leclerc, E., Maekawa, T., Kinoshita, H., Shinohara, M., Komori, K., Sakai, Y., and Fujii, T.: "Visualization of oxygen gradient in a PDMS hepatocyte culture device", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.411-412.
  • Komeya, M., Kimura, H., Fujii, T., and Ogawa, T.: "A novel microfluidic device for organ culture: in vitro spermatogenesis on chip", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.505-506.
  • Shinha, K., Horayama, M., Fujii, T., and Kimura, H.: "Development of a microfluidic probe integrated device toward cell-based assays", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.932-933.
  • Hsu, R. C., Kinoshita, H., Asaoka, R., Aihara, M., and Fujii, T.: "Development and demonstration of microfluidic glaucoma drainage device", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.1324-1325.
  • Nishida, S., Matsubara, N., Fukuba, T., Kyo, M., and Fujii, T.: "Underwater atomic force microscope for in situ nanoscale imaging in deep sea", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.1398-1399.
  • Fukuba, T., Hanatani, K., Okamura, K., and Fujii, T.: "Microfluidic device for in situ quantification of marine microbial ATP with in-line photolysis of caged ATP as internal standard", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.1469-1470.
  • Antfolk, M., Kim, S. H., Koizumi, S., Kaneda, S., Fujii, T., and Laurell, T.: "An integrated acousto- and dielectrophoresis device for tumor cell separation, concentration, and single-cell trapping", Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland (2016), pp.1657-1658.
  • 金秀炫,小泉沙織,藤井輝夫:"マイクロ流体アプローチによる1 細胞アッセイ技術の開発",細胞アッセイ技術の現状と将来,東京(2016).
  • 西田周平,松原直貴,福場辰洋,許正憲,藤井輝夫:"海中原子間力顕微鏡の実海域実証試験",ブルーアース2016 要旨集,東京(2016),pp.55-56.
  • 松本倫実,E. Leclerc,前川敏郎,木下晴之,篠原満利恵,小森喜久夫,酒井康行,藤井輝夫:"肝細胞培養マイクロデバイス内における酸素濃度可視化手法の基礎的検証",2016年度精密工学会春季大会学術講演会講演論文集,千葉(2016),pp.301-302.
  • 花谷耕平,福場辰洋,岡村慶,藤井輝夫:"Caged ATPを用いた深海微生物ATPセンサの現場校正システム",2016年度精密工学会春季大会学術講演会講演論文集,千葉(2016),pp.495-496.
  • Kim, S. H., and Fujii, T.:"Single-cell analysis of rare cancer cells using a microfluidic device",第75回日本癌学会学術総会,横浜(2016).
  • Kozuka, M., Takagi, H., Ito, H., Kim, S.-H., Hirai, M., and Fujii, T.:"Genetic testing by a novel high-purity concentration system for circulating tumor cells independent of epithelial markers",第75回日本癌学会学術総会,横浜(2016).
  • Ito, H., Kim, S.-H., Kozuka, M., Takagi, H., Hirai, M., and Fujii, T.:"Development of a negative selection method-based technology to purify and enrich circulating tumor cells",第75回日本癌学会学術総会,横浜(2016).
  • Takagi, H., Kozuka, M., Ito, H., Kim, S.-H., Hirai, M., and Fujii, T.:"Development of method for high-performance filtering and detecting circulating tumor cells",第75回日本癌学会学術総会,横浜(2016).
  • 福場辰洋,下島公紀,岡村慶,藤井輝夫:"深海pH計測の為の現場校正機能付きpHセンサの開発",第33回「センサ・マイクロマシンと応用システム」シンポジウム論文集,長崎(2016),25am2-PS-067.
  • 西田周平,松原直貴,藤井輝夫:"海中原子間力顕微鏡-深海における自己検知型カンチレバーの利用-",第33回「センサ・マイクロマシンと応用システム」シンポジウム論文集,長崎(2016),24pm2-B-7.
  • 松本倫実,E. Leclerc,前川敏郎,木下晴之,篠原満利恵,小森喜久夫,酒井康行,藤井輝夫:"肝細胞培養マイクロ流体デバイス内に形成された酸素濃度分布の可視化",化学とマイクロ・ナノシステム学会第33回研究会(33rd CHEMINAS)講演要旨集,東京(2016),p.35.
  • Genot, A., Baccouche, A., Sieskind, R.,Aubert-Kato N., Bredeche, N., Bartolo, J. F, Taly, V., Fujii, T., and Rondelez, Y.:"High-throughput mapping of nonlinear biochemical circuits with droplets",化学とマイクロ・ナノシステム学会第33 回研究会(33rd CHEMINAS)講演要旨集,東京(2016),p.69.
  • 松本倫実,E. Leclerc,前川敏郎,木下晴之,篠原満利恵,小森喜久夫,酒井康行,藤井輝夫:"ガス透過性を低下させたマイクロ流体デバイス内での肝細胞培養条件の決定",化学とマイクロ・ナノシステム学会第34回研究会(34th CHEMINAS)講演要旨集,東京(2016).
  • Baccouche, A., Fujii, T., and Rondelez, Y.: "Microscopic agents programmed by DNA circuits", Proceedings of DNA21, Cambridge, USA (2015).
  • Kim, S. H., and Fujii, T.: "Highly efficient single cell trapping and analysis of small number of cancer cells with a microwell array utilizing electrostatic forces", Abstract book of 2015 meeting on SINGLE CELL ANALYSES, NY, USA (2015), 44.
  • Nishida, S., Matsubara, N., Fujii, T., Fukuba, T., Kyo, M., Okamura, K.,and Shitashima, K.: "Underwater atomic force microscopy for in situ observation of micro- organisms in the deep sea", Proceedings of International Symposium on Underwater Technology 2015 (UT15), Chennai, India (2015), UT15-171.
  • Hanatani, K., Fujii, T., and Fukuba, T.: "Development of in-situ microbial ATP analyzer and internal standard calibration method", Proceedings of International Symposium on Underwater Technology 2015 (UT15), Chennai, India (2015), UT15-120.
  • Kim, S. H., and Fujii, T.: "Highly efficient trapping and analysis of rare cells using an electroactive double-well array", Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Gyeongju, KOREA (2015), pp.73-75.
  • Kim, S. H., Antfok, M., Jonsson, L., Koizumi, S., Kaneda, S., Fujii, T., and Laurell, T.: "Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level", Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015) , Gyeongju, KOREA (2015), pp.346-348.
  • Levi, T., Tixier-Mita, A., Ségard, B.-D., Toshiyoshi, H., Fujita, H., and Fujii, T.: "Biomimetic microfluidic neurons for hybrid experiments",Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Gyeongju, KOREA (2015), pp.546-548.
  • Nukaga, M., Kim, S. H., Yahata, K., Fujii, T., Kaneko, O., and Kimura, H.: "On-chip deformability measurement of malaria parasite-infected red blood cells by dielectrophoretic force",Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015) Gyeongju, KOREA (2015), pp.484-486.
  • Hibara, A., Miyazaki, K., Fukuba, T., and Fujii, T.: "Phase separation method for aqueous samples containing unknown ratio of organic phases", Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015) Gyeongju, KOREA (2015), pp.1993-1995.
  • Kim, S. H. and Fujii, T.: "Highly efficient single cell trapping and analysis of small number of cancer cells with a microwell array utilizing electrostatic forces", Abstract book of 2015 meeting on SINGLE CELL ANALYSES, NY, USA (2015), pp.44.
  • Nishida, S., Matsubara, N., Fukuba, T., Kyo, M., and Fujii, T.: "Underwater Atomic Force Microscope - Towards in situ nanoscale measurements in deep sea", Proceedings of OCEANS'15, Maryland, USA (2015), pp.150523-119.
  • Gines, G., Zadorin, A., Fujii,T., and Rondelez, Y.: "Microscopic Agents Programmed by DNA Circuits", The 20th International Conference on DNA Computing and Molecular Programming (DNA21), MA, USA (2015).
  • 金秀炫,藤井輝夫:"Electroactive Double-Well Array を用いた希少細胞の1細胞解析",2015年度精密工学会秋季大会学術講演会講演論文集,仙台(2015),pp.783-784.
  • 徐若棋,木下晴之,朝岡亮,相原一,藤井輝夫:"緑内障インプラントデバイスのためのマイクロバルブの改良",2015年度精密工学会秋季大会学術講演会講演論文集,仙台(2015),pp.819-820.
  • 前川敏郎,木下晴之,藤井輝夫:"マイクロ流体細胞培養システムを用いた分子濃度の時空間的制御",化学とマイクロ・ナノシステム学会第32回研究会(32nd CHEMINAS)講演要旨集,福岡(2015),p.33.
  • 緒方謙,金秀炫,藤井輝夫:"エレクトロアクティブマイクロウェルアレイを用いた高効率1細胞解析",化学とマイクロ・ナノシステム学会第32回研究会(32nd CHEMINAS)講演要旨集,福岡(2015),p.34.
  • 金秀炫,小泉沙織,藤井輝夫:"希少細胞の1細胞アッセイのためのダブルウェルアレイの開発",化学とマイクロ・ナノシステム学会第32 回研究会(32nd CHEMINAS)講演要旨集,福岡(2015),p.76.
  • 松本倫実,前川敏郎,E. Leclerc,酒井康行,藤井輝夫:"肝細胞培養マイクロデバイスにおける酸素濃度勾配の形成",第16回公益社団法人計測自動制御学会システムインテグレーション部門講演会SI2015予稿集,名古屋(2015),pp.669-672.
  • 木下晴之,榊原隆,大島まり,藤井輝夫:"マイクロハイドロ−リックソフトアクチュエータの基盤技術の構築",第16回公益社団法人計測自動制御学会システムインテグレーション部門講演会SI2015予稿集,名古屋(2015),pp.1536-1539.