研究業績

書籍、レビュー論文、原著論文、学会発表など

最近の業績の一部を挙げています。
さらに過去の文献や講演に関する情報については「業績一覧」のページをご覧ください。


書籍、レビュー論文

  • 木村啓志,酒井康行,藤井輝夫:"マイクロ流体デバイス技術によるOrgan/Body-on-a-Chipの実現に向けた取り組み",細胞,Vol.43, No.3 (2016),pp.44-47.
  • 藤井輝夫:"年頭所感",生産研究,Vol.68, No.1 (2016),pp.1-2.
  • 木村啓志,酒井康行、藤井輝夫:"マイクロ流体デバイス技術によるOrgan/Body-on-a-Chipの実現に向けた取り組み",細胞,Vol.43, No.3 (2016) pp.44-47.
  • 木村啓志,藤井輝夫,酒井康行:"創薬を加速化するツールとしてのOrgan-on-a-chip の進展",薬剤学,Vol.76, No.4 (2016) pp.238-242.
  • 小森喜久夫,木村啓志,藤井輝夫,酒井康行:"細胞アッセイ応用を指向した生理学的応答を示す臓器・生体モデルの開発",化学センサ,Vol.3,No.3 (2016) pp.104-110.
  • Kawada, J., Kaneda, S., Kim, S.-H., and Fujii, T.: "Microfluidic Approach to Cell Handling and Measurement", Tsuji, S., and Sone, J. eds., Intelligent Nanosystems for Innovations in Energy, Environment, and Biotechnologies, Springer (2016), pp.85-106
  • 福場辰洋,花谷耕平,藤井輝夫:"マイクロ流体デバイス技術を応用した現場計測システム",光アライアンス,Vol.26,No.5 (2015),pp.7-11.
  • 福場辰洋,西田周平,藤井輝夫:"可搬型装置が拓く資源探査・海洋科学の新時代",化学工学誌,Vol.79,No.2 (2015),pp.125-127.
  • 藤井輝夫:"『「いきもの」に学ぶ工学』所長挨拶",生産研究,Vol.67,No.5 (2015),pp.1-3.
  • ナタリーフランセス,金範?,藤田博之,エリックラルティゴー,藤井輝夫,ドミニクコラール:"Sendng Microsystems in Medicine in Lille – European Japanese Technologies against Cancer A blank is missing (SMMiL-E)",生産研究,Vol.67,No.5 (2015),pp.131-134.
  • ティモテレヴィ,藤井輝夫:"Microfluidic device that mimics neurons",生産研究,Vol.67,No.5 (2015),pp.135-137.
  • アレクサンドルバクーシュ,藤井輝夫,ヤニックロンドレーズ,アントニージュノ:"Molecular programming and microsystems",生産研究,Vol.67,No.5 (2015),pp.169-175.
  • Fukuba, T., Noguchi, T., and Fujii, T.: "The Yoron Hole: The Shallowest Hydrothermal System in the Okinawa Trough", J. Ishibashi, K. Okino, and M. Sunamura eds., Subseafloor Biosphere Linked to Hydrothermal Systems - TAIGA Concept, Springer (2015), pp.489-492, DOI: 10.1007/978-4-431-54865-2_38
  • Fukuba, T., Noguchi, T., and Fujii, T.: "The Irabu Knoll: Hydrothermal Site at the Edge of the Yaeyama Graben", J. Ishibashi, K. Okino, and M. Sunamura eds., Subseafloor Biosphere Linked to Hydrothermal Systems - TAIGA Concept, Springer (2015), pp.493-496, DOI: 10.1007/978-4-431-54865-2_39
  • Noguchi, T., Fukuba, T., Okamura, K., Ijiri, A., Yanagawa, K., Ishitani, Y., Fujii, T., and Sunamura, M.: "Distribution and Biogeochemical Properties of Hydrothermal Plumes in the Rodoriguez Triple Junction", J. Ishibashi, K. Okino, and M. Sunamura eds., Subseafloor Biosphere Linked to Hydrothermal Systems - TAIGA Concept, Springer (2015), pp.195-204,DOI: 10.1007/978-4-431-54865-2_15

原著論文

  • Baccouche A., Okumura S., Sieskind R., Henry E., Aubert-Kato N., Bredeche N., Bartolo JF., Taly V., Rondelez Y., Fujii T., Genot A. J.: "Massively parallel and multiparameter titration of biochemical assays with droplet microfluidics", Nature Protocols 12, 1912 (2017), doi:10.1038/nprot.2017.092.
  • Kaneda, S., Kawada, J., Akutsu, H., Ichida, J., Ikeuchi, Y., and Fujii, T.: "Compartmentalized embryoid body culture for induction of spatially patterned differentiation", Biomicrofluidics, Vol.11 (2017), 041101.
  • Gines, G., Zadorin, A., Galas, J.-C., Fujii, T., Extevez-Torres, A., and Rondelez, Y.: "Microscopic Agents Programmed by DNA Circuits", Nature Nanotechnology (2017), advanced online publication, doi:10.1038/nnano.2016.299
  • Leclerc, E., Kimura, K. Shinohara, M., Mathies D., Le Gall, M., Kido, A., Miyajima, A., Fuii, T. Sakai, Y.: "Comparison of the Transcriptomic Profile of Hepatic Human induced Pluripotent Stem like Cells Cultured in Petri and in a 3D Microscale Dynamic Environment", Genomics, Vol.109 (2017), pp.16-26
  • Antfolk, M, Kim, S.-H., Koizumi, S., Fujii, T., and Laurell, T.: "Label-free single-cell separation and imaging of cancer cells using an integrated microfluidic system", Scientific Reports (2017), 7:46507 | DOI: 10.1038/srep46507
  • Komeya, M., Hiroshi Kimura, H., Nakamura, H., Yokonishi, T., Sato, T., Kojima, K., Hayashi, K., Katagiri, K., Yamanaka, H., Sanjo, H., Yao, M., Kamimura, S., Inoue, K., Ogonuki, N., Ogura, A., Fujii, T., and Ogawa, T.: "Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device", Sci Rep., Vol. 19(6) (2016), pp. 2147232(8).
  • Perret, G., Ginet, P., Tarhan, M. C., Baccouche, A., Lacornerie, T., Kumemura, M., Jalabert, L., Cleri, F., Lartigau, E. F., Kim, B. J., Karsten, S. L., Fujita, H., Rondelez, Y., Fujii, T., and Collard, D.: "Nano systems and devices for applications in biology and nanotechnology", Solid-State Electronics, Vol.115 (2016), pp.66-73.
  • Kim, Y.J., Kim, S.H., Fujii, T., and T. Matsunaga, Y.: "Dual Stimuli-Responsive Smart Beads that allow "On-Off" Manipulation of Cancer Cells", Biomaterials Science, Vol.4 (2016), pp.953-957.
  • Kim, S.-H., and Fujii, T.: "Efficient Analysis of a Small Number of Cancer Cells at the Single-cell Level using Electroactive Double-well Array", Lab on a Chip, Vol.16 (2016) pp.2440-2449, featured as Front Cover, p.2351, DOI: 10.1039/C6LC90066F
  • Genot, A., Baccouche, A., Sieskind, R., Aubert-Kato, N., Bredeche, N., Bartolo, J.-F. Taly, V., Fujii, T., and Rondelez, Y.: "High-resolution mapping of bifurcations in nonlinear biochemical circuits", Nature Chemistry, Vol.8 (2016), pp.760-767.
  • Park, J.-W., Kim, S.-H., Ito, T., Fujii, T., Kim, S.-Y., Laurell, T., Lee, S.-W. and Goda, K.: "Acoustofluidic harvesting of microalgae on a single chip", Biomicrofluidics, Vol.10 (2016), 034119.
  • Levi, T., and Fujii, T.: "Microfluidic neurons, a new way in neuromorphic engineering?", Micromachines, Vol.7 (2016), 146, doi:10.3390/mi7080146.
  • Montagne, K., Gines, G., Fujii, T., and Rondelez, Y.: "Boosting functionality of synthetic DNA circuits with tailored deactivation", Nature Communications, Vol.7 (2016), 13474, DOI: 10.1038/ncomms13474
  • Horayama, M., Kabayama, K., Fujii, T., and Kimura, H.: "Spatial Chemical Stimulation Control in Microenvironment by Microfluidic Probe Integrated Device for Cell-based Assay", PLoS ONE, Vol.11, No.12 (2016), e0168158. doi:10.1371/journal. pone.0168158
  • Kim, S. H., Antfolk, M., Kobayashi, M., Kaneda, S., Laurell, T., and Fujii, T.: "Highly efficient single cell arraying by integrating acoustophoretic cell pre-concentration and dielectrophoretic cell trapping", Lab on a Chip, Vol.15 (2015), pp.4356-4365.
  • Kobayashi, M., Kim, S. H., Nakamura, H., Kaneda, S., and Fujii, T.: "Cancer cell analyses at the single cell-level using electroactive microwell array device", PLoS ONE, Vol.10(11) (2015), e0139980, pp.1-11.
  • Provin, C., Nicolas, A., Grégoire, S., and Fujii, T.: "A Microfluidic Diffusion Cell for Fast and Easy Percutaneous Absorption Assays", Pharm Res, Vol. 32(8) (2015), pp.2704-12.
  • Tozawa, H., Maekawa, T., Sakai, T., and Fujii, T.: "A novel effect of parylene-based surface coating on HepG2 cell func- tion", Materials Science and Engineering C, Vol.46 (2015), pp.190-194.

招待講演、依頼講演

  • Fujii, T.: "Microfluidics as Innovative Technology for Biological Experimentations", The 3rd Symposium Max Planck-the University of Tokyo Center for Inflammology, Berlin(2016)
  • 金田祥平:"細胞培養・分離・解析用マイクロ流体技術",次世代マイクロ化学チップコンソーシアム第37回研究会,東京 (2016).
  • 藤井輝夫:"マイクロ流体デバイス技術が拓く医療バイオ分野の新展開",第12回骨免疫ワークショップ,東京 (2016).
  • 藤井輝夫:"Small Meets Large: Connecting Microfluidics with Marine Ecology",OISTミニシンポジウム,沖縄 (2015).
  • 藤井輝夫:"マイクロ流体デバイスを用いた細胞培養技術",筋萎縮性側索硬化症(ALS)新規治療法開発をめざした病態解明平成27年度ワークショップ,東京 (2015).
  • 藤井輝夫:"細胞・組織工学のための高解像度バイオ技術",ライフサイエンス技術部会材料分科会講演会,東京 (2015).

学会発表

  • Nishida, S., Matsubara, N., Fujii, T., Fukuba, T., Kyo, M., Okamura, K.,and Shitashima, K.: "Underwater atomic force microscopy for in situ observation of micro- organisms in the deep sea", Proceedings of International Symposium on Underwater Technology 2015 (UT15), Chennai, India (2015), UT15-171.
  • Hanatani, K., Fujii, T., and Fukuba, T.: "Development of in-situ microbial ATP analyzer and internal standard calibration method", Proceedings of International Symposium on Under- water Technology 2015 (UT15), Chennai, India (2015), UT15-120.
  • Kim, S. H., and Fujii, T.: "Highly efficient trapping and analysis of rare cells using an electroactive double-well array", Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Gyeongju, KOREA (2015), pp.73-75.
  • Kim, S. H., Antfok, M., Jonsson, L., Koizumi, S., Kaneda, S., Fujii, T., and Laurell, T.: "Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level", Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015) , Gyeongju, KOREA (2015), pp. 346-348.
  • Levi, T., Tixier-Mita, A., Ségard, B.-D., Toshiyoshi, H., Fujita, H., and Fujii, T.: "Biomimetic microfluidic neurons for hybrid experiments",Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Gyeongju, KOREA (2015), pp.546-548.
  • Nukaga, M., Kim, S. H., Yahata, K., Fujii, T., Kaneko, O., and Kimura, H.: "On-chip deformability measurement of malaria parasite-infected red blood cells by dielectrophoretic force",Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015) Gyeongju, KOREA (2015), pp.484-486.
  • Hibara, A., Miyazaki, K., Fukuba, T., and Fujii, T.: "Phase separation method for aqueous samples containing unknown ratio of organic phases", Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015) Gyeongju, KOREA (2015), pp.1993-1995.
  • Kim, S. H. and Fujii, T.: "Highly efficient single cell trapping and analysis of small number of cancer cells with a microwell array utilizing electrostatic forces", Abstract book of 2015 meeting on SINGLE CELL ANALYSES, NY, USA (2015), pp.44.
  • Nishida, S., Matsubara, N., Fukuba, T., Kyo, M., and Fujii, T.: "Underwater Atomic Force Microscope - Towards in situ nanoscale measurements in deep sea", Proceedings of OCEANS'15, Maryland, USA (2015), pp.150523-119.
  • Gines, G., Zadorin, A., Fujii,T., and Rondelez, Y.: "Microscopic Agents Programmed by DNA Circuits", The 20th International Conference on DNA Computing and Molecular Programming (DNA21), MA, USA (2015).