Our group has been studying on microfluidic devices since established in 1999. Microfluidic device is a tiny chip that contains micro- or nano-sized fluidic channels, fabricated with microelectromechanical systems (MEMS) techniques. The microfluidic device has been used for a miniaturized biochemical analysis system so-called Micro Total Analysis System (μTAS).
One of the most important features of microfluidic devices is the use of an extremely tiny volume for biochemical reactions. For instance, the use of microfluidic channels or microchambers allows rapid mixing of reagents, low reagent consumption, efficient reactions and highly sensitive detection. Such tiny reaction volume also facilitates parallelization of reaction for high-throughput analysis. Moreover, precisely controllable laminar flow in the microfluidic device efficiently manipulates various reagents and precisely controls the biochemical reactions. These features of microfluidic devices allow more precise and efficient biochemical analysis, compared with a conventional bulk system.
Additionally, due to the small size of the system, the microfluidic device can be utilized for the development of a portable health care system allowing continuous monitoring of one’s health, point-of-care device for complex medical testing at home, or in situ analysis system for a measurement and analysis of target samples in an extreme environment such as deep see or space.
Teruo Fujii, Professor
Head of Applied Microfluidic Systems Lab.